Thrombospondin-1 opens the paracellular pathway in pulmonary microvascular endothelia through EGFR/ErbB2 activation

Thrombospondin-1 (TSP1) is a multidomain protein that contains epidermal growth factor (EGF)-like repeats that indirectly activate the EGF receptor (EGFR) and selected downstream signaling pathways. In these studies, we show that TSP1 opens the paracellular pathway in human lung microvascular endoth...

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Main Authors: Garg, Pallavi, Yang, Shiqi, Liu, Anguo, Pallero, Manuel A., Buchsbaum, Donald J., Mosher, Deane F., Murphy-Ullrich, Joanne E., Goldblum, Simeon E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129900/
https://ncbi.nlm.nih.gov/pubmed/21531776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00287.2010
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