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Cyclophilin D and the mitochondrial permeability transition in kidney proximal tubules after hypoxic and ischemic injury

Mitochondrial matrix cyclophilin D (CyPD) is known to promote development of the mitochondrial permeability transition (MPT). Kidney proximal tubule cells are especially prone to deleterious effects of mitochondrial damage because of their dependence on oxidative mitochondrial metabolism for ATP pro...

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Detalhes bibliográficos
Main Authors: Park, Jeong Soon, Pasupulati, Ratna, Feldkamp, Thorsten, Roeser, Nancy F., Weinberg, Joel M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129895/
https://ncbi.nlm.nih.gov/pubmed/21490135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00033.2011
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