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Diet-induced obesity leads to the development of leptin resistance in vagal afferent neurons

Ingestion of high-fat, high-calorie diets is associated with hyperphagia, increased body fat, and obesity. The mechanisms responsible are currently unclear; however, altered leptin signaling may be an important factor. Vagal afferent neurons (VAN) integrate signals from the gut in response to ingest...

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Detalhes bibliográficos
Main Authors: de Lartigue, Guillaume, Barbier de la Serre, Claire, Espero, Elvis, Lee, Jennifer, Raybould, Helen E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129833/
https://ncbi.nlm.nih.gov/pubmed/21521717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00056.2011
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