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Interventional MRI-guided Putaminal Delivery of AAV2-GDNF for a Planned Clinical Trial in Parkinson's Disease

Clinical trials involving direct infusion of neurotrophic therapies for Parkinson's disease (PD) have suffered from poor coverage of the putamen. The planned use of a novel interventional-magnetic resonance imaging (iMRI) targeting system for achieving precise, real-time convection-enhanced del...

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Detalhes bibliográficos
Main Authors: Richardson, R Mark, Kells, Adrian P, Rosenbluth, Kathryn H, Salegio, Ernesto Aguilar, Fiandaca, Massimo S, Larson, Paul S, Starr, Philip A, Martin, Alastair J, Lonser, Russell R, Federoff, Howard J, Forsayeth, John R, Bankiewicz, Krystof S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129792/
https://ncbi.nlm.nih.gov/pubmed/21343917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.11
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