Reduced thermotolerance in aged cells results from a loss of an hsp72- mediated control of JNK signaling pathway

Aged organisms exhibit a greatly decreased ability to induce the major heat shock protein, Hsp72, in response to stresses, a phenomenon that can also be observed in cell cultures (Heydari AR, Takahashi R, Gutsmann A, You S and Richardson A (1994) Hsp70 and aging. Experientia 50: 1092–1098). Hsp72 wa...

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Bibliografiske detaljer
Udgivet i:Cell Stress Chaperones
Main Authors: Volloch, Vladimir, Mosser, Dick D., Massie, Bernard, Sherman, Michael Y.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 1998
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312972/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9880239/
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