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Reduced expression of SynGAP, a neuronal GTPase-activating protein, enhances capsaicin-induced peripheral sensitization

Synaptic GTPase-activating protein (SynGAP) is a neuronal-specific Ras/Rap-GAP that increases the hydrolysis rate of GTP to GDP, converting Ras/Rap from the active into the inactive form. The Ras protein family modulates a wide range of cellular pathways including those involved in sensitization of...

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Detalhes bibliográficos
Main Authors: Duarte, Djane Braz, Duan, Jian-Hong, Nicol, Grant D., Vasko, Michael R., Hingtgen, Cynthia M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129716/
https://ncbi.nlm.nih.gov/pubmed/21525372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00963.2010
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