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SynGAP regulates synaptic strength and mitogen-activated protein kinases in cultured neurons

Silent synapses, or excitatory synapses that lack functional α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs), are thought to be critical for regulation of neuronal circuits and synaptic plasticity. Here, we report that SynGAP, an excitatory synapse-specific RasGAP, regulates...

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Detalhes bibliográficos
Main Authors: Rumbaugh, Gavin, Adams, J. Paige, Kim, Jee H., Huganir, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450173/
https://ncbi.nlm.nih.gov/pubmed/16537406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600084103
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