Antitumor activity of mutant bacterial cytosine deaminase gene for colon cancer

AIM: To evaluate bacterial cytosine deaminase (bCD) mutant D314A and 5-fluorocytosine (5-FC) for treatment of colon cancer in a mouse model. METHODS: Recombinant lentivirus vectors that contained wild-type bCD gene (bCDwt), and bCD mutant D314A gene (bCD-D314A) with green fluorescence protein gene w...

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Detalhes bibliográficos
Main Authors: Deng, Long-Ying, Wang, Jian-Ping, Gui, Zhi-Fu, Shen, Li-Zong
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2011
Assuntos:
Brief Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129511/
https://ncbi.nlm.nih.gov/pubmed/21734808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v17.i24.2958
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