TLR2-dependent Modulation of Osteoclastogenesis by Porphyromonas gingivalis through Differential Induction of NFATc1 and NF-κB

Osteolytic diseases, including rheumatoid arthritis, osteomyelitis, and periodontitis, are usually associated with bacterial infections. However, the precise mechanisms by which bacteria induce bone loss still remain unclear. Evidence exists that Toll-like receptor (TLR) signaling regulates both inf...

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Bibliografiske detaljer
Main Authors: Zhang, Ping, Liu, Jianzhong, Xu, Qingan, Harber, Gregory, Feng, Xu, Michalek, Suzanne M., Katz, Jenny
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129197/
https://ncbi.nlm.nih.gov/pubmed/21566133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198085
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