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TLR2-dependent Modulation of Osteoclastogenesis by Porphyromonas gingivalis through Differential Induction of NFATc1 and NF-κB

Osteolytic diseases, including rheumatoid arthritis, osteomyelitis, and periodontitis, are usually associated with bacterial infections. However, the precise mechanisms by which bacteria induce bone loss still remain unclear. Evidence exists that Toll-like receptor (TLR) signaling regulates both inf...

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Autori principali: Zhang, Ping, Liu, Jianzhong, Xu, Qingan, Harber, Gregory, Feng, Xu, Michalek, Suzanne M., Katz, Jenny
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129197/
https://ncbi.nlm.nih.gov/pubmed/21566133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198085
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