Krüppel-like Factor 4 (KLF4) Activates the Transcription of the Gene for the Platelet Isoform of Phosphofructokinase (PFKP) in Breast Cancer

Krüppel-like factor 4 (KLF4) is a transcription factor that plays an important role in cell differentiation, proliferation, and survival, especially in the context of cancers. This study revealed that KLF4 activates glycolytic metabolism in breast cancer cells by up-regulating the platelet isoform o...

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Main Authors: Moon, Jong-Seok, Kim, Hee Eun, Koh, Eunjin, Park, Se Ho, Jin, Won-Ji, Park, Byeong-Woo, Park, Sahng Wook, Kim, Kyung-Sup
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Gene Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129162/
https://ncbi.nlm.nih.gov/pubmed/21586797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.236737
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