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Substrate-dependent Gating of Anion Channels Associated with Excitatory Amino Acid Transporter 4

EAAT glutamate transporters do not only function as secondary-active glutamate transporters but also as anion channels. EAAT anion channel activity depends on transport substrates. For most isoforms, it is negligible without external Na(+) and increased by external glutamate. We here investigated ga...

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Autori principali: Machtens, Jan-Philipp, Kovermann, Peter, Fahlke, Christoph
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129159/
https://ncbi.nlm.nih.gov/pubmed/21572047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.207514
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