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Induced fit substrate binding to an archeal glutamate transporter homologue

Excitatory amino acid transporters (EAATs) are a class of glutamate transporters that terminate glutamatergic synaptic transmission in the mammalian CNS. Glt(Ph), an archeal EAAT homolog from Pyrococcus horikoshii, is currently the only member with a known 3D structure. Here, we studied the kinetics...

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מידע ביבליוגרפי
Main Authors: Ewers, David, Becher, Toni, Machtens, Jan-Philipp, Weyand, Ingo, Fahlke, Christoph
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725095/
https://ncbi.nlm.nih.gov/pubmed/23840066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300772110
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