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Human Interleukin-1 Receptor-associated Kinase-2 Is Essential for Toll-like Receptor-mediated Transcriptional and Post-transcriptional Regulation of Tumor Necrosis Factor α

Toll-like receptors (TLRs) are pattern-recognition receptors that recognize microbial ligands and subsequently trigger intracellular signaling pathways involving transcription factors such as NFκB and MAPKs such as p38. TLR signaling can regulate both transcriptional and post-transcriptional events...

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書誌詳細
主要な著者: Flannery, Sinead M., Keating, Sinead E., Szymak, Joanna, Bowie, Andrew G.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129149/
https://ncbi.nlm.nih.gov/pubmed/21606490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.248351
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