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Beyond αβ/γδ lineage commitment: TCR signal strength regulates γδ T cell maturation and effector fate
Signaling by the γδ T cell receptor (TCR) is required not only for αβ/γδ lineage commitment but also to activate and elicit effector functions in mature γδ T cells. Notably, at both of these stages, the signal delivered by the γδTCR is more robust than the one delivered by either the preTCR or the α...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129014/ https://ncbi.nlm.nih.gov/pubmed/20452783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2010.04.006 |
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