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Beyond αβ/γδ lineage commitment: TCR signal strength regulates γδ T cell maturation and effector fate

Signaling by the γδ T cell receptor (TCR) is required not only for αβ/γδ lineage commitment but also to activate and elicit effector functions in mature γδ T cells. Notably, at both of these stages, the signal delivered by the γδTCR is more robust than the one delivered by either the preTCR or the α...

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Autors principals: Hayes, Sandra M., Laird, Renee M., Love, Paul E.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129014/
https://ncbi.nlm.nih.gov/pubmed/20452783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2010.04.006
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