טוען...
A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance
To identify key connections between DNA-damage repair and checkpoint pathways, we performed RNA interference screens for regulators of the ionizing radiation-induced G2 checkpoint, and we identified the breast cancer gene BRCA2. The checkpoint was also abrogated following depletion of PALB2, an inte...
שמור ב:
| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128973/ https://ncbi.nlm.nih.gov/pubmed/21637299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.99 |
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