Single-molecule approach to immunoprecipitated protein complexes: insights into miRNA uridylation

Single-molecule techniques have been used for only a subset of biological problems because of difficulties in studying proteins that require cofactors or post-translational modifications. Here, we present a new method integrating single-molecule fluorescence microscopy and immunopurification to stud...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yeom, Kyu-Hyeon, Heo, Inha, Lee, Jinwoo, Hohng, Sungchul, Kim, V Narry, Joo, Chirlmin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
Schlagworte:
Scientific Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128948/
https://ncbi.nlm.nih.gov/pubmed/21637296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.100
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