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Single-molecule pull-down for investigating protein–nucleic acid interactions

The genome and transcriptome are constantly modified by proteins in the cell. Recent advances in single-molecule techniques allow for high spatial and temporal observations of these interactions between proteins and nucleic acids. However, due to the difficulty of obtaining functional protein comple...

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Bibliographic Details
Published in:Methods
Main Authors: Fareh, Mohamed, Loeff, Luuk, Szczepaniak, Malwina, Haagsma, Anna C., Yeom, Kyu-Hyeon, Joo, Chirlmin
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408933/
https://ncbi.nlm.nih.gov/pubmed/27017911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.03.022
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