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Copper-catalyzed Synthesis of 2,4-Disubstituted Allenoates from α-Diazoesters

[Image: see text] A Cu-catalyzed method for coupling α-substituted-α-diazoesters with terminal alkynes to give substituted allenoates is described. Key to the development of a selective method was the recognition that an adventitous base catalyzes the isomerization to form the allenoate product. A p...

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Detalles Bibliográficos
Main Authors: Hassink, Matthew, Liu, Xiaozhong, Fox, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128944/
https://ncbi.nlm.nih.gov/pubmed/21486078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol2006242
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