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GroEL binds a late folding intermediate of phage P22 coat protein

GroEL recognizes proteins that are folding improperly or that have aggregation-prone intermediates. Here we have used as substrates for GroEL, wildtype (WT) coat protein of phage P22 and 3 coat proteins that carry single amino acid substitutions leading to a temperature-sensitive folding (tsf) pheno...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Stress Chaperones
Hauptverfasser: de Beus, Mitchel D, Doyle, Shannon M, Teschke, Carolyn M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312882/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11005374/
https://ncbi.nlm.nih.govhttps://doi.org/10.1379/1466-1268(2000)005<0163:gbalfi>2.0.co;2
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