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GroEL binds a late folding intermediate of phage P22 coat protein

GroEL recognizes proteins that are folding improperly or that have aggregation-prone intermediates. Here we have used as substrates for GroEL, wildtype (WT) coat protein of phage P22 and 3 coat proteins that carry single amino acid substitutions leading to a temperature-sensitive folding (tsf) pheno...

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Detalhes bibliográficos
Main Authors: de Beus, Mitchel D, Doyle, Shannon M, Teschke, Carolyn M
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Stress Society International 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312882/
https://ncbi.nlm.nih.gov/pubmed/11005374
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