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Chromatin-specific regulation of LEF-1–β-catenin transcription activation and inhibition in vitro
Transcriptional activation of Wnt/Wg-responsive genes requires the stabilization and nuclear accumulation of β-catenin, a dedicated coactivator of LEF/TCF enhancer-binding proteins. Here we report that recombinant β-catenin strongly enhances binding and transactivation by LEF-1 on chromatin template...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312851/ https://ncbi.nlm.nih.gov/pubmed/11751639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.946501 |
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