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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

Adenocarcinoma of the lung is the most common form of lung cancer, but the cell of origin and the stages of progression of this tumor type are not well understood. We have developed a new model of lung adenocarcinoma in mice harboring a conditionally activatable allele of oncogenic K-ras. Here we sh...

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Autors principals: Jackson, Erica L., Willis, Nicholas, Mercer, Kim, Bronson, Roderick T., Crowley, Denise, Montoya, Raymond, Jacks, Tyler, Tuveson, David A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC312845/
https://ncbi.nlm.nih.gov/pubmed/11751630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.943001
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