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Chromatin “Pre-Pattern” and Histone Modifiers in a Fate Choice for Liver and Pancreas

Transcriptionally silent genes can be marked by histone modifications and regulatory proteins that indicate the genes’ potential to be activated. Such marks have been identified in pluripotent cells, but it is unknown how such marks occur in descendant, multipotent embryonic cells that have restrict...

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Detalhes bibliográficos
Main Authors: Xu, Cheng-Ran, Cole, Philip A., Meyers, David J., Kormish, Jay, Dent, Sharon, Zaret, Kenneth S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128430/
https://ncbi.nlm.nih.gov/pubmed/21596989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1202845
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