PIASy, a nuclear matrix–associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

The Wnt-responsive transcription factor LEF1 can activate transcription in association with β-catenin and repress transcription in association with Groucho. In search of additional regulatory mechanisms of LEF1 function, we identified the protein inhibitor of activated STAT, PIASy, as a novel intera...

Full beskrivning

Bibliografiska uppgifter

I publikationen:	Genes Dev
Huvudupphov:	Sachdev, Shrikesh, Bruhn, Laurakay, Sieber, Heidemarie, Pichler, Andrea, Melchior, Frauke, Grosschedl, Rudolf
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Cold Spring Harbor Laboratory Press 2001
Ämnen:	Research Paper
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312834/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11731474/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.944801
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!