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Clinical effect of increasing doses of lenalidomide in high-risk myelodysplastic syndrome and acute myeloid leukemia with chromosome 5 abnormalities

BACKGROUND: Patients with chromosome 5 abnormalities and high-risk myelodysplastic syndromes or acute myeloid leukemia have a poor outcome. We hypothesized that increasing doses of lenalidomide may benefit this group of patients by inhibiting the tumor clone, as assessed by fluorescence in situ hybr...

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Detalhes bibliográficos
Main Authors: Möllgård, Lars, Saft, Leonie, Treppendahl, Marianne Bach, Dybedal, Ingunn, Nørgaard, Jan Maxwell, Astermark, Jan, Ejerblad, Elisabeth, Garelius, Hege, Dufva, Inge Høgh, Jansson, Monika, Jädersten, Martin, Kjeldsen, Lars, Linder, Olle, Nilsson, Lars, Vestergaard, Hanne, Porwit, Anna, Grønbæk, Kirsten, Lindberg, Eva Hellström
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128214/
https://ncbi.nlm.nih.gov/pubmed/21719884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.039669
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