Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression

Clonal heterogeneity has not been described in patients with myelodysplastic syndrome with isolated del(5q), for which lenalidomide has emerged as a highly potent treatment. However, transformation to acute myeloid leukemia is occasionally observed, particularly in patients without a cytogenetic res...

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Bibliografske podrobnosti
Main Authors: Jädersten, Martin, Saft, Leonie, Pellagatti, Andrea, Göhring, Gudrun, Wainscoat, James S., Boultwood, Jacqueline, Porwit, Anna, Schlegelberger, Brigitte, Hellström-Lindberg, Eva
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2009
Teme:
Brief Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791931/
https://ncbi.nlm.nih.gov/pubmed/19797731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.011528
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