Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML

Deletions of chromosome 5q are associated with poor outcomes in acute myeloid leukemia (AML) suggesting the presence of tumor suppressor(s) at the locus. However, definitive identification of putative tumor suppressor genes remains controversial. Here we show that a 106-nucleotide noncoding RNA vaul...

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Detaylı Bibliyografya
Asıl Yazarlar: Treppendahl, Marianne Bach, Qiu, Xiangning, Søgaard, Alexandra, Yang, Xiaojing, Nandrup-Bus, Cecilie, Hother, Christoffer, Andersen, Mette Klarskov, Kjeldsen, Lars, Möllgaard, Lars, Hellström-Lindberg, Eva, Jendholm, Johan, Porse, Bo T., Jones, Peter A., Liang, Gangning, Grønbæk, Kirsten
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2012
Konular:
Myeloid Neoplasia
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251229/
https://ncbi.nlm.nih.gov/pubmed/22058117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-362541
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