Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML

Deletions of chromosome 5q are associated with poor outcomes in acute myeloid leukemia (AML) suggesting the presence of tumor suppressor(s) at the locus. However, definitive identification of putative tumor suppressor genes remains controversial. Here we show that a 106-nucleotide noncoding RNA vaul...

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Detalhes bibliográficos
Main Authors: Treppendahl, Marianne Bach, Qiu, Xiangning, Søgaard, Alexandra, Yang, Xiaojing, Nandrup-Bus, Cecilie, Hother, Christoffer, Andersen, Mette Klarskov, Kjeldsen, Lars, Möllgaard, Lars, Hellström-Lindberg, Eva, Jendholm, Johan, Porse, Bo T., Jones, Peter A., Liang, Gangning, Grønbæk, Kirsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251229/
https://ncbi.nlm.nih.gov/pubmed/22058117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-362541
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