Coilin forms the bridge between Cajal bodies and SMN, the Spinal Muscular Atrophy protein

Spinal muscular atrophy (SMA) is a genetic disorder caused by mutations in the human survival of motor neuron 1 gene, SMN1. SMN protein is part of a large complex that is required for biogenesis of various small nuclear ribonucleoproteins (snRNPs). Here, we report that SMN interacts directly with th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hebert, Michael D., Szymczyk, Piotr W., Shpargel, Karl B., Matera, A. Gregory
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2001
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC312817/
https://ncbi.nlm.nih.gov/pubmed/11641277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.908401
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