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A Drosophila melanogaster model of spinal muscular atrophy reveals a function for SMN in striated muscle

Mutations in human survival motor neurons 1 (SMN1) cause spinal muscular atrophy (SMA) and are associated with defects in assembly of small nuclear ribonucleoproteins (snRNPs) in vitro. However, the etiological link between snRNPs and SMA is unclear. We have developed a Drosophila melanogaster syste...

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Bibliografiske detaljer
Main Authors: Rajendra, T.K., Gonsalvez, Graydon B., Walker, Michael P., Shpargel, Karl B., Salz, Helen K., Matera, A. Gregory
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064057/
https://ncbi.nlm.nih.gov/pubmed/17353360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200610053
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