Residual Cajal bodies in coilin knockout mice fail to recruit Sm snRNPs and SMN, the spinal muscular atrophy gene product

Cajal bodies (CBs) are nuclear suborganelles involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs). In addition to snRNPs, they are highly enriched in basal transcription and cell cycle factors, the nucleolar proteins fibrillarin (Fb) and Nopp140 (Nopp), the survival motor neuron (...

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Main Authors: Tucker, Karen E., Berciano, Maria Teresa, Jacobs, Erica Y., LePage, David F., Shpargel, Karl B., Rossire, Jennifer J., Chan, Edward K.L., Lafarga, Miguel, Conlon, Ronald A., Matera, A. Gregory
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2001
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150753/
https://ncbi.nlm.nih.gov/pubmed/11470819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200104083
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