Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN

Smad proteins mediate transforming growth factor-β (TGF-β) signaling to regulate cell growth and differentiation. SnoN is an important negative regulator of TGF-β signaling that functions to maintain the repressed state of TGF-β target genes in the absence of ligand. On TGF-β stimulation, Smad3 and...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Stroschein, Shannon L., Bonni, Shirin, Wrana, Jeffrey L., Luo, Kunxin
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2001
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312804/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11691834/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.912901
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