Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN

Smad proteins mediate transforming growth factor-β (TGF-β) signaling to regulate cell growth and differentiation. SnoN is an important negative regulator of TGF-β signaling that functions to maintain the repressed state of TGF-β target genes in the absence of ligand. On TGF-β stimulation, Smad3 and...

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Bibliographic Details
Main Authors: Stroschein, Shannon L., Bonni, Shirin, Wrana, Jeffrey L., Luo, Kunxin
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2001
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC312804/
https://ncbi.nlm.nih.gov/pubmed/11691834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.912901
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