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SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor β signaling

Transforming growth factor β (TGF-β) regulates a variety of physiologic processes, including growth inhibition, differentiation, and induction of apoptosis. Some TGF-β-initiated signals are conveyed through Smad3; TGF-β binding to its receptors induces phosphorylation of Smad3, which then migrates t...

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Bibliografiske detaljer
Main Authors: Sun, Yin, Liu, Xuedong, Ng-Eaton, Elinor, Lodish, Harvey F., Weinberg, Robert A.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22943/
https://ncbi.nlm.nih.gov/pubmed/10535941
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