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Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN
Smad proteins mediate transforming growth factor-β (TGF-β) signaling to regulate cell growth and differentiation. SnoN is an important negative regulator of TGF-β signaling that functions to maintain the repressed state of TGF-β target genes in the absence of ligand. On TGF-β stimulation, Smad3 and...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312804/ https://ncbi.nlm.nih.gov/pubmed/11691834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.912901 |
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