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Hypoxia in cartilage: HIF-1α is essential for chondrocyte growth arrest and survival
Breakdown or absence of vascular oxygen delivery is a hallmark of many common human diseases, including cancer, myocardial infarction, and stroke. The chief mediator of hypoxic response in mammalian tissues is the transcription factor hypoxia-inducible factor 1 (HIF-1), and its oxygen-sensitive comp...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312800/ https://ncbi.nlm.nih.gov/pubmed/11691837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.934301 |
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