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Drosophila Separase is required for sister chromatid separation and binds to PIM and THR

Drosophila PIM and THR are required for sister chromatid separation in mitosis and associate in vivo. Neither of these two proteins shares significant sequence similarity with known proteins. However, PIM has functional similarities with securin proteins. Like securin, PIM is degraded at the metapha...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Principais autores: Jäger, Hubert, Herzig, Alf, Lehner, Christian F., Heidmann, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312799/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11581162/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.207301
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