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Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis

The establishment of metaphase chromosomes is an essential prerequisite of sister chromatid separation in anaphase. It involves the coordinated action of cohesin and condensin, protein complexes that mediate cohesion and condensation, respectively. In metazoans, most cohesin dissociates from chromat...

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Autors principals: Losada, Ana, Hirano, Michiko, Hirano, Tatsuya
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC187494/
https://ncbi.nlm.nih.gov/pubmed/12464631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.249202
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