Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs

Evidence of endoplasmic reticulum (ER) stress has been found in lungs of patients with familial and sporadic idiopathic pulmonary fibrosis. We tested whether ER stress causes or exacerbates lung fibrosis by (i) conditional expression of a mutant form of surfactant protein C (L188Q SFTPC) found in fa...

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書誌詳細
主要な著者: Lawson, William E., Cheng, Dong-Sheng, Degryse, Amber L., Tanjore, Harikrishna, Polosukhin, Vasiliy V., Xu, Xiaochuan C., Newcomb, Dawn C., Jones, Brittany R., Roldan, Juan, Lane, Kirk B., Morrisey, Edward E., Beers, Michael F., Yull, Fiona E., Blackwell, Timothy S.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2011
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127925/
https://ncbi.nlm.nih.gov/pubmed/21670280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107559108
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