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B regulatory cells and the tumor-promoting actions of TNF-α during squamous carcinogenesis

The inflammatory cytokine TNF-α has been recognized as a critical tumor promoter, but the effector cells that mediate its action have not been fully characterized. Because B cells regulate squamous and prostate carcinogenesis, and Tnf(−/−) mice harbor B-cell defects, we investigated the hypothesis t...

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Main Authors: Schioppa, Tiziana, Moore, Robert, Thompson, Richard G., Rosser, Elizabeth C., Kulbe, Hagen, Nedospasov, Sergei, Mauri, Claudia, Coussens, Lisa M., Balkwill, Frances R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127875/
https://ncbi.nlm.nih.gov/pubmed/21670304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100994108
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