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Compromised Function of Regulatory T Cells in Rheumatoid Arthritis and Reversal by Anti-TNFα Therapy

Regulatory T cells have been clearly implicated in the control of disease in murine models of autoimmunity. The paucity of data regarding the role of these lymphocytes in human autoimmune disease has prompted us to examine their function in patients with rheumatoid arthritis (RA). Regulatory (CD4(+)...

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Autors principals: Ehrenstein, Michael R., Evans, Jamie G., Singh, Animesh, Moore, Samantha, Warnes, Gary, Isenberg, David A., Mauri, Claudia
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211983/
https://ncbi.nlm.nih.gov/pubmed/15280421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040165
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