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Compromised Function of Regulatory T Cells in Rheumatoid Arthritis and Reversal by Anti-TNFα Therapy

Regulatory T cells have been clearly implicated in the control of disease in murine models of autoimmunity. The paucity of data regarding the role of these lymphocytes in human autoimmune disease has prompted us to examine their function in patients with rheumatoid arthritis (RA). Regulatory (CD4(+)...

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Detalhes bibliográficos
Main Authors: Ehrenstein, Michael R., Evans, Jamie G., Singh, Animesh, Moore, Samantha, Warnes, Gary, Isenberg, David A., Mauri, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211983/
https://ncbi.nlm.nih.gov/pubmed/15280421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040165
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