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The yeast Xrs2 complex functions in S phase checkpoint regulation
The Nbs1 complex is an evolutionarily conserved multisubunit nuclease composed of the Mre11, Rad50, and Nbs1 proteins. Hypomorphic mutations in the NBS1 or MRE11 genes in humans result in conditions characterized by DNA damage sensitivity, cell cycle checkpoint deficiency, and high cancer incidence....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2001
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312768/ https://ncbi.nlm.nih.gov/pubmed/11544181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.208701 |
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