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Rad9 BRCT domain interaction with phosphorylated H2AX regulates the G1 checkpoint in budding yeast
Phosphorylation of histone H2A or H2AX is an early and sensitive marker of DNA damage in eukaryotic cells, although mutation of the conserved damage-dependent phosphorylation site is well tolerated. Here, we show that H2A phosphorylation is required for cell-cycle arrest in response to DNA damage at...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1973948/ https://ncbi.nlm.nih.gov/pubmed/17721446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401036 |
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