Senescent cells develop a PARP-1 and nuclear factor-κB-associated secretome (PNAS)

Melanoma cells can enter the process of senescence, but whether they express a secretory phenotype, as reported for other cells, is undetermined. This is of paramount importance, because this secretome can alter the tumor microenvironment and the response to chemotherapeutic drugs. More generally, t...

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Detalhes bibliográficos
Main Authors: Ohanna, Mickaël, Giuliano, Sandy, Bonet, Caroline, Imbert, Véronique, Hofman, Véronique, Zangari, Joséphine, Bille, Karine, Robert, Caroline, Bressac-de Paillerets, Brigitte, Hofman, Paul, Rocchi, Stéphane, Peyron, Jean-François, Lacour, Jean-Philippe, Ballotti, Robert, Bertolotto, Corine
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127427/
https://ncbi.nlm.nih.gov/pubmed/21646373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.625811
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