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The Regulatory Mechanisms of Tumor Suppressor P16(INK4A) and Relevance to Cancer

P16(INK4A) (also known as P16 and MTS1), a protein consisting exclusively of four ankyrin repeats, is recognized as a tumor suppressor mainly due to the prevalence of genetic inactivation of the p16(INK4A) (or CDKN2A) gene in virtually all types of human cancers. However, it has also been shown that...

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Hlavní autoři: Li, Junan, Poi, Ming Jye, Tsai, Ming-Daw
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127263/
https://ncbi.nlm.nih.gov/pubmed/21619050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200642e
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