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Evidence that P12, a specific variant of P16(INK4A), plays a suppressive role in human pancreatic carcinogenesis
The INK4a-ARF locus plays a central role in the development of pancreatic tumors as evidenced by the fact that up to 98% of pancreatic tumor specimens harbored genetic alterations at the INK4a-ARF locus. Interestingly, in addition to the well-known P16(INK4A) (P16) and P14ARF tumor suppressors, the...
में बचाया:
| मुख्य लेखकों: | , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2013
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752424/ https://ncbi.nlm.nih.gov/pubmed/23727582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.05.078 |
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