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Tumor suppressor INK4: refinement of p16INK4A structure and determination of p15INK4B structure by comparative modeling and NMR data.

Within the tumor suppressor protein INK4 (inhibitor of cyclin-dependent kinase 4) family, p15INK4B is the smallest and the only one whose structure has not been determined previously, probably due to the protein's conformational flexibility and instability. In this work, multidimensional NMR st...

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Autori principali: Yuan, C., Selby, T. L., Li, J., Byeon, I. J., Tsai, M. D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144649/
https://ncbi.nlm.nih.gov/pubmed/10892805
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