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Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function

In Saccharomyces cerevisiae, Pds1 is an anaphase inhibitor and plays an essential role in DNA damage and spindle checkpoint pathways. Pds1 is phosphorylated in response to DNA damage but not spindle disruption, indicating distinct mechanisms delaying anaphase entry. Phosphorylation of Pds1 is Mec1 a...

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Detalles Bibliográficos
Autores principales: Wang, Hong, Liu, Dou, Wang, Yanchang, Qin, Jun, Elledge, Stephen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC312708/
https://ncbi.nlm.nih.gov/pubmed/11390356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.893201
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