The elusive role of the SPRY2 domain in RyR1

The second of three SPRY domains (SPRY2, S(1085)-V(1208)) located in the skeletal muscle ryanodine receptor (RyR1) is contained within regions of RyR1 that influence EC coupling and bind to imperatoxin A, a toxin probe of RyR1 channel gating. We examined the binding of the F loop (P(1107)-A(1121)) i...

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Detalhes bibliográficos
Main Authors: Tae, HanShen, Wei, Lan, Willemse, Hermia, Mirza, Shamaruh, Gallant, Esther M, Board, Philip G, Dirksen, Robert T, Casarotto, Marco G, Dulhunty, Angela F
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127056/
https://ncbi.nlm.nih.gov/pubmed/21239886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.5.2.14407
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