Functional implications of modifying RyR-activating peptides for membrane permeability

1. Our aim was to determine whether lipoamino acid conjugation of peptides that are high-affinity activators of ryanodine receptor (RyR) channels would (a) render the peptides membrane permeable, (b) alter their structure or (a) reduce their activity. The peptides correspond to the A region of the I...

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Bibliographische Detailangaben
Hauptverfasser: Dulhunty, Angela F, Cengia, Louise, Young, Jacqui, Pace, Suzy M, Harvey, Peta J, Lamb, Graham D, Chan, Yiu-Ngok, Wimmer, Norbert, Toth, Istvan, Casarotto, Marco G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
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Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576055/
https://ncbi.nlm.nih.gov/pubmed/15778698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705981
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